Archive for the 'Research' Category

Oct 27 2011

CDC Recommends Boys Receive HPV Vaccine

Filed under Penile Warts,Research

CDC Recommends Boys Receive HPV Vaccine

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Apr 13 2011

Asymptomatic HSV-2 Carriers May Transmit Genital Herpes

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Asymptomatic HSV-2 Carriers May Transmit Genital Herpes

Researchers at the University of Washington have found just how easily people infected with herpes simplex type 2 virus, which causes genital herpes, can unknowingly pass it on to other people.  On average, the researchers found those “who had had past herpes outbreaks were infectious 20.1% of the time, while the asymptomatic group was found to be able to transmit the virus 10.2% of time.”  Virus presence was detected “at least once in 83.4% of the people with symptomatic infection and in 68.2% of people with asymptomatic herpes.” The authors say the study shows that even people with asymptomatic herpes type 2 “can transmit it to a sexual partner.”

This further means that pregnant women with no symptoms can pass on the virus to their babies with devastating consequences for the newborn, including death.  Moreover, HSV-2 infection can cause complications in people who have weakened immune systems due to chronic disease, and it can increase a person’s likelihood of contracting HIV.

Condom use, drug therapy and disclosure of the disease to partners can help curb the spread of herpes.  A blood tests to detect HSV-2 became widely available in 1999, making it easier for people to find out if they have genital herpes even if the infection isn’t active.

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Dec 27 2010

FDA Approves HPV Vaccine for MEN!!!

Filed under General Info,Research

FDA Approves HPV Vaccine for MEN!!!

Gardasil (human papillomavirus vaccine), the vaccine that can prevent most cases of cervical cancer in girls, has won the FDA’s blessing as a vaccine to prevent anal cancer, a huge victory for men!

The FDA’s  approval for Gardasil as an anal cancer vaccine opens the way for the medication’s maker, Merck and Co. Inc., to market the vaccine to boys and young men between the ages of nine and 26 – an option that will be most meaningful for men who have sex with men, but valuable to all.  Nobody likes getting HPV on their penis.  It really can devastate many boys and men.  When the HPV ends up on their anal area – the risk of anal cancer is high.  Although this is most commonly seen in homosexual men, it is not infrequent for heterosexual men to be at risk.  It is easy to imagine how HPV can start on the shaft, and with a scratch here, and an itch there – end up on the back side.

This is a great win for men – and we hope that the approval by the FDA will quickly translate to coverage amongst insurance companies to make the vaccine accessible quickly to this new population.

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Jan 30 2010

Oral Sex Cause of Throat Cancer Rise

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Oral Sex Cause of Throat Cancer Rise

Changing sexual practices have led to a dramatic rise in throat cancer in the United States over the past two decades, and experts say they fear an epidemic of the disease.

The comments were made Wednesday at a news conference held by the American Association for Cancer Research to discuss research into the role of the sexually transmitted human papilloma virus ( HPV) in head and neck cancer.

Increasing rates of HPV infection, spread through oral sex, is largely driving the rapid rise in oropharyngeal cancers, which include tumors of the throat, tonsils, and base of the tongue, said Scott Lippman, MD, who chairs the thoracic department at the University of Texas M.D. Anderson Cancer Center.

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Jun 16 2009

The Male Pap Smear

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The Male Pap Smear

In a study published in The New England Journal of Medicine, gay and bisexual men were found to have a significantly higher risk for developing anal cancer, over thirty-five times greater than the general population. HIV-positive men were estimated to be eighty times more likely to get it. Although anal cancer accounts for less than 5 percent of all digestive and intestinal tract cancers, the rates have increased 160 percent over a thirty- year period. Gay African-American men have the sharpest increase and the lowest survival rates. Interestingly, anal cancer in gay men is as common as cervical cancer was in women before the use of the Pap smear, the test that screens for precancerous lesions on the cervix. Both types of cancer are caused by the human papillomavirus (HPV), which also causes anal and genital warts. HPV is one of the most common STDs in the world. Fortunately, anal cancer is highly preventable and treatable if caught in time.

There are more then one hundred different subtypes of HPV, and some are the source of common warts as seen on the hands and feet. HPV affects approximately 65 percent of HIV-negative gay men, and nearly 95 percent of HIV-positive gay men carry HPV in their anal canals. Most do not even know they have it. Subtypes 6 and 11 cause 90 percent of genital warts, while subtypes 16 and 18 are far more dangerous because of their precancerous potential.

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Mar 12 2009

Using Liquid Nitrogen To Treat HPV

Filed under General Info,Research

Using Liquid Nitrogen To Treat HPV

by: Michelle Lipke

Liquid nitrogen is a popular destructive treatment for warts.  It is readily available in both dermatology and primary care offices.   Verucca-Freeze and many similar brands available over the counter are a liquid applied from a spray can, but only freeze to -70C.  Warts may not resolve with the over the counter freezing due to the fact that they do not freeze as fast as the liquid nitrogen available in the clinic setting; as well as the proper application technique may not always be used. The wart virus, known as human papilloma virus (HPV), is not destroyed by the freezing procedure.   Liquid nitrogen freezes at -196C and works by destroying the skin cells which in turn release the wart virus.  They body responds to this process by causing an immune response to resolve the wart.

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Nov 29 2008

A Vaccine for Boys to Help Girls?

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A Vaccine for Boys to Help Girls?

As a parent of a school-age daughter, I haven’t decided what to think about the new cervical cancer vaccine. That’s why I was interested to learn the shot may soon be given to boys primarily to benefit girls.

Merck’s Gardasil vaccine is approved for use in girls and women, ages 9 to 26, to protect them against the human papillomavirus, or H.P.V., which causes cervical cancer. Girls can be vaccinated when they are as young as 9, although it’s recommended for 11- and 12-year-olds, before they are sexually active.

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Nov 16 2008

Spermicides May Help Warts Spread

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Spermicides May Help Warts Spread

A common ingredient found in over-the-counter vaginal spermicides may ease the transmission of human papillomavirus or HPV infection, at least in animals, according to a new study.

HPV infection causes genital warts and the majority of cervical cancers.

“Spermicides containing nonoxynol-9 may enhance the ability of the HPV to take hold in the genital tract, at least in animals,” says researchers at the National Cancer Institute at the National Institutes of Health in Bethesda, Md.  The study appears in the July issue of Nature Medicine.  Here is the original paper.

As this study was not in humans, it needs further research.   Nonoxynol-9 is found in lubricants, contraceptive jellies and creams, and other birth control products. In recent years, its use has been found in some studies to boost the risk of transmission of HIV, the virus that causes AIDS.

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